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Reaction Explorer: Organic Chemistry Tutorials Reaction Explorer is an interactive system for learning and practicing reactions, syntheses and mechanisms in organic chemistry, with advanced support for the automatic generation of random problems, curved-arrow mechanism diagrams, and inquiry-based learning.   Reaction Drills: Single-Step Reaction Completion Reaction Drills produce a series of (ungraded) reaction equations with one hidden component (reactant, reagent or product) and asks you to mentally "fill-in-the-blank" to test and train your skill, similar to flashcards.   Synthesis Explorer: Multi-Step Synthesis Design The primary interface for solving multi-step synthesis design problems and for freely exploring different reactant and reagent combinations.   Mechanism Explorer: Arrow-Pushing Mechanism Diagrams Reactions support curved-arrow mechanism diagram viewing and exploration to not only show "what" a reaction will produce, but to also explain "how" the reaction will proceed.   User Records: Problem Completion Records Review your past problem completion record and check your progress towards completing any class requirements here.	Support & Updates Tutorials and Walkthroughs Unsure where to start? Tutorials and FAQs will walk you through the most common tasks. Introduction Video Usage Instructions Video Help Recent Forum Topics Currently unavailable Top User Leaderboards Top Users this Past Year by Synthesis Problems (Non-Random) Rank User ID Metric 1 9____645 41 2 9____968 35 3 8____725 31 3 8____100 31 5 1____992 30 5 6____257 30 5 1____971 30 5 5____008 30 5 1____157 30 5 7____421 30 Publication An article describing the background, functions and usage results of this tutorial system has been published in the Journal of Chemical Education. Mirror Servers The system should automatically assign you to an available server, but if you encounter slow response times, try accessing one of the mirror servers directly. Mirror #1 Mirror #2 Mirror #3 Mirror #4 Contact Info If you encounter any issues, please send me an e-mail at chenjh (at) uci.edu so I can continue to improve this system for you. Acknowledgements OpenEye Scientific Software Provider of software tools and components, including OEChem, Ogham and LexiChem. JME Editor (Peter Ertl, Novartis) Molecule editing Java Applet to enable sketching of your own reactants. ChemAxon Molecular visualization applet, including 3D views and mechanism arrow diagram sketching.
Reaction Drills Top Reaction List (Generate Random Reactions) [Smith 7.00, Loudon 9.00, Solomons 6.15] Substitution vs. Elimination [Smith 8.00, Loudon 9.50, Solomons 6.15] Substitution and Elimination 'Tricks' [Smith 9.00, Loudon 10.00, Solomons 11.00] Alcohol Substitution [Smith 9.50, Loudon 11.00, Solomons 11.00] Alcohol Dehydration and Epoxides [Smith 10.00, Loudon 5.00, Solomons 8.02] Alkene Addition [Smith 11.00, Loudon 14.00] Alkynes [Smith 12.00, Loudon 14.06, Solomons 12.04] Redox of Alkenes and Alkynes [Smith 20.07, Loudon 21.09, Solomons 12.04] Redox of Alcohols and Carbonyls [Smith 15.00, Loudon 17.02, Solomons 10.00] Alkanes, Radical Reactions [Smith 16.00, Loudon 15.00, Solomons 13.00] Dienes, Conjugation, Diels-Alder [Smith 18.00, Loudon 16.04, Solomons 15.00] Electrophilic Aromatic Substitution [Smith 18.06, Loudon 16.05, Solomons 15.09] EAS Substituent Effects [Smith 18.14, Loudon 17.05, Solomons 15.15] Reactions of Substituted Benzenes [Smith 20.14, Loudon 11.04, Solomons 12.05] Epoxides and Organometallic Compounds [Smith 20.15, Loudon 22.10, Solomons 19.09] Organometallic Addition, Conjugate Addition [Smith 21.00, Loudon 19.00, Solomons 16.00] Aldehydes and Ketones [Smith 21.15, Loudon 21.09, Solomons 19.09] Protecting Groups and Hydride Addition [Smith 22.00, Loudon 21.00, Solomons 18.00] Carboxylic Acid Derivatives [Smith 23.00, Loudon 22.00, Solomons 17.00] Enolate Chemistry [Smith 23.09, Loudon 22.00, Solomons 19.03] Acetoacetic and Malonic Ester Synthesis [Smith 24.00, Loudon 22.04, Solomons 17.04] Aldol Chemistry [Smith 24.05, Loudon 22.05, Solomons 19.02] Claisen Condensation [Smith 25.00, Loudon 23.00, Solomons 20.00] Amines [Smith 25.14, Loudon 23.10, Solomons 20.06] Arenediazonium [Smith 26.00, Loudon 18.00, Solomons 21.20] Transition Metal Catalysis [Smith 27.00, Loudon 27.00, Solomons 22.00] Carbohydrates [Smith 28.02, Loudon 26.04, Solomons 24.03] Amino Acid Synthesis [Smith 28.06, Loudon 26.07, Solomons 25.05] Peptide Synthesis [Loudon 18.04, Solomons 21.11] SnAr, Benzyne Reactions [Loudon 25.00, Solomons 21.20] Pericyclic Reactions [Loudon 24.05] Pyridine Derivatives [Loudon 24.00] Naphthalene and Heteroaromatic EAS Textbook Any Smith 2nd ed. Loudon 4th ed. Solomons 9th ed. Vollhardt 5th ed. Bruice 4th ed. Reaction Subject Category Smith 7.00 - Substitution (Nucleophilic) of Alkyl Halides Smith 8.00 - Elimination Reactions of Alkyl Halides Smith 9.00 - Alcohols and Epoxides Smith 10.00 - Alkenes, Electrophilic Addition Smith 11.00 - Alkynes, Addition and Acetylide Ions Smith 12.00 - Redox of Alkenes and Alkynes Smith 12.12 - Oxidation of Alcohols and Alkenes Smith 15.00 - Alkanes, Radical Reactions Smith 16.00 - Dienes, Conjugation, Diels-Alder Smith 18.00 - Electrophilic Aromatic Substitution Smith 18.14 - Reactions of Substituted Benzenes Smith 20.12 - Redox of Alcohols and Carbonyls Smith 20.14 - Epoxides and Organometallic Compounds Smith 20.15 - Organometallic Addition, Conjugate Addition Smith 21.00 - Aldehydes and Ketones Smith 21.15 - Protecting Groups and Hydride Addition Smith 22.00 - Carboxylic Acid Derivatives Smith 23.00 - Enolate Chemistry Smith 23.09 - Acetoacetic and Malonic Ester Synthesis Smith 24.00 - Aldol Chemistry and Michael Addition Smith 24.05 - Claisen Condensations Smith 25.00 - Amines Smith 25.14 - Arenediazonium Reactions Smith 27.00 - Carbohydrates Smith 28.02 - Amino Acid Synthesis Smith 28.06 - Peptide Synthesis Loudon 5.00 - Alkenes Loudon 9.04 - Substitution (Nucleophilic) of Alkyl Halides Loudon 9.05 - Elimination Reactions of Alkyl Halides Loudon 10.00 - Alcohols and Epoxides Loudon 11.04 - Epoxides and Organometallic Compounds Loudon 11.05 - Oxidation of Alcohols and Alkenes Loudon 14.00 - Alkynes Loudon 15.00 - Dienes, Conjugation, Diels-Alder Loudon 16.00 - Electrophilic Aromatic Substitution Loudon 17.00 - Allylic and Benzylic Reactivity Loudon 17.02 - Alkanes, Radical Reactions Loudon 18.00 - Transition Metal (Pd) Catalysis Loudon 18.04 - SnAr and Benzyne Reactions Loudon 19.00 - Aldehydes and Ketones Loudon 20.10 - Redox of Alcohols and Carbonyls Loudon 21.00 - Carboxylic Acid Derivatives Loudon 22.00 - Acetoacetic and Malonic Ester Synthesis Loudon 22.00 - Enolate Chemistry Loudon 22.04 - Aldol Chemistry and Michael Addition Loudon 22.05 - Claisen Condensations Loudon 22.08 - Organometallic Addition, Conjugate Addition Loudon 23.00 - Amines Loudon 23.10 - Arenediazonium Reactions Loudon 24.00 - Naphthalene and Heteroaromatic EAS Reactions Loudon 24.05 - Pyridine Derivatives Loudon 25.00 - Pericyclic Reactions Loudon 26.04 - Amino Acid Synthesis Loudon 26.07 - Peptide Synthesis Loudon 27.00 - Carbohydrates Solomons 6.02 - Substitution (Nucleophilic) of Alkyl Halides Solomons 6.15 - Elimination Reactions of Alkyl Halides Solomons 8.02 - Alkenes, Electrophilic Addition Solomons 8.16 - Redox of Alkenes and Alkynes Solomons 8.18 - Alkynes, Addition and Acetylide Ions Solomons 10.00 - Alkanes, Radical Reactions Solomons 11.00 - Alcohols and Epoxides Solomons 12.03 - Redox of Alcohols and Carbonyls Solomons 12.04 - Oxidation of Alcohols and Alkenes Solomons 12.05 - Epoxides and Organometallic Compounds Solomons 13.00 - Dienes, Conjugation, Diels-Alder Solomons 15.00 - Electrophilic Aromatic Substitution Solomons 15.09 - Reactions of Substituted Benzenes Solomons 15.15 - Allylic and Benzylic Reactivity Solomons 16.00 - Aldehydes and Ketones Solomons 17.00 - Enolate Chemistry Solomons 17.04 - Aldol Chemistry and Michael Addition Solomons 18.00 - Carboxylic Acid Derivatives Solomons 19.02 - Claisen Condensations Solomons 19.03 - Acetoacetic and Malonic Ester Synthesis Solomons 19.09 - Organometallic Addition, Conjugate Addition Solomons 20.00 - Amines Solomons 20.06 - Arenediazonium Reactions Solomons 21.11 - SnAr and Benzyne Reactions Solomons 21.20 - Transition Metal (Pd) Catalysis Solomons 21.20 - Pericyclic Reactions Solomons 22.00 - Carbohydrates Solomons 24.03 - Amino Acid Synthesis Solomons 25.05 - Peptide Synthesis Vollhardt 3.00 - Alkanes, Radical Reactions Vollhardt 6.00 - Substitution (Nucleophilic) of Alkyl Halides Vollhardt 7.00 - Elimination Reactions of Alkyl Halides Vollhardt 9.00 - Oxidation of Alcohols and Alkenes Vollhardt 9.00 - Alcohols and Epoxides Vollhardt 12.00 - Alkenes Vollhardt 13.00 - Alkynes Vollhardt 13.50 - Redox of Alkenes and Alkynes Vollhardt 14.00 - Dienes, Conjugation, Diels-Alder Vollhardt 15.00 - Electrophilic Aromatic Substitution Vollhardt 17.00 - Aldehydes and Ketones Vollhardt 18.00 - Enolate Chemistry Vollhardt 18.50 - Organometallic Addition, Conjugate Addition Vollhardt 18.50 - Aldol Chemistry and Michael Addition Vollhardt 19.50 - Redox of Alcohols and Carbonyls Vollhardt 20.00 - Carboxylic Acid Derivatives Vollhardt 21.00 - Amines Vollhardt 22.00 - Reactions of Substituted Benzenes Vollhardt 22.50 - Arenediazonium Reactions Vollhardt 23.00 - Claisen Condensations Vollhardt 23.50 - Acetoacetic and Malonic Ester Synthesis Vollhardt 24.00 - Carbohydrates Vollhardt 26.00 - Amino Acid Synthesis Vollhardt 26.50 - Peptide Synthesis Bruice 4.00 - Alkenes Bruice 6.00 - Alkynes Bruice 8.00 - Dienes, Conjugation, Diels-Alder Bruice 9.00 - Alkanes, Radical Reactions Bruice 10.00 - Substitution (Nucleophilic) of Alkyl Halides Bruice 11.00 - Elimination Reactions of Alkyl Halides Bruice 12.00 - Alcohols and Epoxides Bruice 12.50 - Epoxides and Organometallic Compounds Bruice 15.00 - Electrophilic Aromatic Substitution Bruice 16.00 - Reactions of Substituted Benzenes Bruice 16.50 - Arenediazonium Reactions Bruice 16.75 - SnAr and Benzyne Reactions Bruice 17.00 - Carboxylic Acid Derivatives Bruice 18.00 - Aldehydes and Ketones Bruice 18.50 - Organometallic Addition, Conjugate Addition Bruice 18.80 - Protecting Groups and Hydride Addition Bruice 19.00 - Acetoacetic and Malonic Ester Synthesis Bruice 19.00 - Enolate Chemistry Bruice 19.50 - Claisen Condensations Bruice 19.50 - Aldol Chemistry and Michael Addition Bruice 20.00 - Redox of Alkenes and Alkynes Bruice 20.50 - Redox of Alcohols and Carbonyls Bruice 20.50 - Oxidation of Alcohols and Alkenes Bruice 21.00 - Amines Bruice 21.09 - Naphthalene and Heteroaromatic EAS Reactions Bruice 21.10 - Pyridine Derivatives Bruice 22.00 - Carbohydrates Bruice 23.00 - Peptide Synthesis Bruice 23.00 - Amino Acid Synthesis Bruice 29.00 - Pericyclic Reactions Components to Predict Any Reactants Reagent Products None	Not sure what parameters you need to setup a problem? Click on the Help link above for a general overview of the system, or point your cursor at any control and a brief description will appear here.
Synthesis Explorer Top User ID User Class -- Select -- Chem 51B - Winter 2009 - Freeman Chem 51B - Winter 2009 - King Chem 51B - Winter 2009 - Shea Chem 52B - Winter 2009 - Overman Chem 51A - 2008 - Examples Chem 51B - 2008 - Examples Chem 51C - 2008 - Examples Chem 52A - 2008 - Examples Chem 52B - 2008 - Examples Chem 52C - 2008 - Examples Chem 51A - 2008 - Recommended Chem 51B - 2008 - Recommended Chem 51C - 2008 - Recommended Chem 52A - 2008 - Recommended Chem 52B - 2008 - Recommended Chem 52C - 2008 - Recommended Demo Examples Synthesis Problem (Generate Random Synthesis) #006 [Smith 8.05, Loudon 17.03, Solomons 6.15] #278 [Smith 9.12, Loudon 10.03, Solomons 11.00] #279 [Smith 9.13, Loudon 10.03, Solomons 11.00] #290 [Smith 9.15, Loudon 11.04, Solomons 11.00] #031 [Smith 10.14, Loudon 9.05, Solomons 11.00] #025 [Smith 10.15, Loudon 9.05, Solomons 8.02] #543 [Smith 11.05, Loudon 18.02, Solomons 8.02] #044 [Smith 11.12, Loudon 14.07, Solomons 11.00] #058 [Smith 11.12, Loudon 14.07, Solomons 6.02] #020 [Smith 12.05, Loudon 14.08, Solomons 8.16] #026 [Smith 12.09, Loudon 14.06, Solomons 12.04] #024 [Smith 12.10, Loudon 9.05, Solomons 8.16] #046 [Smith 15.07, Loudon 17.02, Solomons 10.00] #277 [Smith 15.10, Loudon 17.02, Solomons 11.00] #005 [Smith 15.13, Loudon 9.04, Solomons 10.00] #043 [Smith 16.10, Loudon 15.04, Solomons 13.00] #042 [Smith 16.10, Loudon 15.04, Solomons 13.00] #034 [Smith 16.14, Loudon 15.03, Solomons 13.00] #035 [Smith 16.14, Loudon 15.03, Solomons 13.00] #059 [Smith 18.10, Loudon 16.05, Solomons 15.00] #060 [Smith 18.13, Loudon 17.04, Solomons 15.00] #039 [Smith 18.13, Loudon 17.02, Solomons 12.04] #125 [Smith 18.14, Loudon 17.05, Solomons 15.09] #037 [Smith 18.14, Loudon 17.05, Solomons 15.15] #293 [Smith 18.14, Loudon 19.12, Solomons 16.00] #040 [Smith 20.11, Loudon 19.09, Solomons 19.09] #054 [Smith 20.12] #023 [Smith 20.12] #021 [Smith 20.13, Loudon 21.10, Solomons 19.09] #295 [Smith 20.14, Loudon 11.04, Solomons 12.05] #041 [Smith 20.14, Loudon 11.04, Solomons 12.05] #289 [Smith 20.14, Loudon 17.02, Solomons 12.05] #022 [Smith 20.15, Loudon 22.10, Solomons 19.09] #135 [Smith 21.00, Loudon 19.00, Solomons 16.00] #028 [Smith 21.10, Loudon 19.13, Solomons 16.00] #029 [Smith 21.12, Loudon 19.11, Solomons 16.00] #030 [Smith 21.12, Loudon 19.11, Solomons 16.00] #027 [Smith 21.15, Loudon 21.09, Solomons 16.00] #055 [Smith 21.15, Loudon 19.10, Solomons 16.00] #545 [Smith 22.08, Loudon 21.08, Solomons 18.00] #126 [Smith 22.08, Loudon 21.08, Solomons 18.00] #291 [Smith 22.18, Loudon 21.09, Solomons 18.00] #294 [Smith 22.18, Loudon 21.07, Solomons 18.00] #056 [Smith 22.18, Loudon 21.09, Solomons 18.00] #124 [Smith 22.18, Loudon 21.07, Solomons 18.00] #057 [Smith 23.07, Loudon 22.03, Solomons 17.00] #061 [Smith 23.08, Loudon 22.07, Solomons 17.00] #062 [Smith 23.09, Loudon 22.07, Solomons 19.03] #063 [Smith 23.10, Loudon 22.07, Solomons 19.03] #067 [Smith 24.04, Loudon 22.04, Solomons 19.09] #096 [Smith 24.04, Loudon 22.04, Solomons 17.04] #066 [Smith 24.06, Loudon 22.05, Solomons 19.02] #064 [Smith 24.08, Loudon 22.08, Solomons 17.04] #097 [Smith 24.09, Loudon 22.08, Solomons 17.04] #065 [Smith 24.09, Loudon 22.08, Solomons 17.04] #091 [Smith 25.07, Loudon 23.11, Solomons 20.00] #090 [Smith 25.07, Loudon 23.11, Solomons 20.00] #088 [Smith 25.12, Loudon 23.08, Solomons 20.00] #095 [Smith 25.14, Loudon 23.10, Solomons 20.06] #094 [Smith 25.14, Loudon 23.10, Solomons 20.06] #089 [Smith 25.14, Loudon 23.10, Solomons 20.06] #121 [Smith 25.15, Loudon 23.10, Solomons 20.06] #047 [Loudon 18.09, Solomons 21.20] #049 [Loudon 18.09, Solomons 21.20] #544 [Smith 26.01] #050 [Smith 26.03, Loudon 18.05, Solomons 21.20] #087 [Smith 26.03, Loudon 22.02, Solomons 21.20] #048 [Loudon 18.05, Solomons 21.20] #051 [Loudon 18.05, Solomons 21.20] #119 [Smith 27.10, Loudon 27.07, Solomons 22.00] #120 [Smith 27.10, Loudon 27.08, Solomons 22.00] #117 [Smith 28.02, Loudon 26.04, Solomons 24.03] #118 [Smith 28.02, Loudon 26.04, Solomons 24.03] #116 [Smith 28.06, Loudon 26.07, Solomons 25.05] #001 [Smith 18.00, Loudon 16.00, Solomons 15.00] #003 [Smith 12.00, Loudon 14.00, Solomons 8.16] #002 [Smith 15.00, Loudon 5.00, Solomons 10.00] #004 [Smith 9.12, Loudon 10.04, Solomons 11.00] #045 [Smith 10.10, Loudon 9.05, Solomons 8.02] #547 [Loudon 23.10, Solomons 21.11] #038 [Loudon 18.04, Solomons 21.11] #292 [Solomons 18.00] #123 [Loudon 25.02, Solomons 21.20] #122 [Loudon 25.04, Solomons 21.20] #093 [Loudon 24.01, Solomons 20.06] #092 [Loudon 24.03, Solomons 21.20] #546 [Loudon 16.05, Solomons 15.09] Textbook Any Smith 2nd ed. Loudon 4th ed. Solomons 9th ed. Vollhardt 5th ed. Bruice 4th ed. Reaction Subject Category Smith 7.00 - Substitution (Nucleophilic) of Alkyl Halides Smith 8.00 - Elimination Reactions of Alkyl Halides Smith 9.00 - Alcohols and Epoxides Smith 10.00 - Alkenes, Electrophilic Addition Smith 11.00 - Alkynes, Addition and Acetylide Ions Smith 12.00 - Redox of Alkenes and Alkynes Smith 12.12 - Oxidation of Alcohols and Alkenes Smith 15.00 - Alkanes, Radical Reactions Smith 16.00 - Dienes, Conjugation, Diels-Alder Smith 18.00 - Electrophilic Aromatic Substitution Smith 18.14 - Reactions of Substituted Benzenes Smith 20.12 - Redox of Alcohols and Carbonyls Smith 20.14 - Epoxides and Organometallic Compounds Smith 20.15 - Organometallic Addition, Conjugate Addition Smith 21.00 - Aldehydes and Ketones Smith 21.15 - Protecting Groups and Hydride Addition Smith 22.00 - Carboxylic Acid Derivatives Smith 23.00 - Enolate Chemistry Smith 23.09 - Acetoacetic and Malonic Ester Synthesis Smith 24.00 - Aldol Chemistry and Michael Addition Smith 24.05 - Claisen Condensations Smith 25.00 - Amines Smith 25.14 - Arenediazonium Reactions Smith 27.00 - Carbohydrates Smith 28.02 - Amino Acid Synthesis Smith 28.06 - Peptide Synthesis Loudon 5.00 - Alkenes Loudon 9.04 - Substitution (Nucleophilic) of Alkyl Halides Loudon 9.05 - Elimination Reactions of Alkyl Halides Loudon 10.00 - Alcohols and Epoxides Loudon 11.04 - Epoxides and Organometallic Compounds Loudon 11.05 - Oxidation of Alcohols and Alkenes Loudon 14.00 - Alkynes Loudon 15.00 - Dienes, Conjugation, Diels-Alder Loudon 16.00 - Electrophilic Aromatic Substitution Loudon 17.00 - Allylic and Benzylic Reactivity Loudon 17.02 - Alkanes, Radical Reactions Loudon 18.00 - Transition Metal (Pd) Catalysis Loudon 18.04 - SnAr and Benzyne Reactions Loudon 19.00 - Aldehydes and Ketones Loudon 20.10 - Redox of Alcohols and Carbonyls Loudon 21.00 - Carboxylic Acid Derivatives Loudon 22.00 - Acetoacetic and Malonic Ester Synthesis Loudon 22.00 - Enolate Chemistry Loudon 22.04 - Aldol Chemistry and Michael Addition Loudon 22.05 - Claisen Condensations Loudon 22.08 - Organometallic Addition, Conjugate Addition Loudon 23.00 - Amines Loudon 23.10 - Arenediazonium Reactions Loudon 24.00 - Naphthalene and Heteroaromatic EAS Reactions Loudon 24.05 - Pyridine Derivatives Loudon 25.00 - Pericyclic Reactions Loudon 26.04 - Amino Acid Synthesis Loudon 26.07 - Peptide Synthesis Loudon 27.00 - Carbohydrates Solomons 6.02 - Substitution (Nucleophilic) of Alkyl Halides Solomons 6.15 - Elimination Reactions of Alkyl Halides Solomons 8.02 - Alkenes, Electrophilic Addition Solomons 8.16 - Redox of Alkenes and Alkynes Solomons 8.18 - Alkynes, Addition and Acetylide Ions Solomons 10.00 - Alkanes, Radical Reactions Solomons 11.00 - Alcohols and Epoxides Solomons 12.03 - Redox of Alcohols and Carbonyls Solomons 12.04 - Oxidation of Alcohols and Alkenes Solomons 12.05 - Epoxides and Organometallic Compounds Solomons 13.00 - Dienes, Conjugation, Diels-Alder Solomons 15.00 - Electrophilic Aromatic Substitution Solomons 15.09 - Reactions of Substituted Benzenes Solomons 15.15 - Allylic and Benzylic Reactivity Solomons 16.00 - Aldehydes and Ketones Solomons 17.00 - Enolate Chemistry Solomons 17.04 - Aldol Chemistry and Michael Addition Solomons 18.00 - Carboxylic Acid Derivatives Solomons 19.02 - Claisen Condensations Solomons 19.03 - Acetoacetic and Malonic Ester Synthesis Solomons 19.09 - Organometallic Addition, Conjugate Addition Solomons 20.00 - Amines Solomons 20.06 - Arenediazonium Reactions Solomons 21.11 - SnAr and Benzyne Reactions Solomons 21.20 - Transition Metal (Pd) Catalysis Solomons 21.20 - Pericyclic Reactions Solomons 22.00 - Carbohydrates Solomons 24.03 - Amino Acid Synthesis Solomons 25.05 - Peptide Synthesis Vollhardt 3.00 - Alkanes, Radical Reactions Vollhardt 6.00 - Substitution (Nucleophilic) of Alkyl Halides Vollhardt 7.00 - Elimination Reactions of Alkyl Halides Vollhardt 9.00 - Oxidation of Alcohols and Alkenes Vollhardt 9.00 - Alcohols and Epoxides Vollhardt 12.00 - Alkenes Vollhardt 13.00 - Alkynes Vollhardt 13.50 - Redox of Alkenes and Alkynes Vollhardt 14.00 - Dienes, Conjugation, Diels-Alder Vollhardt 15.00 - Electrophilic Aromatic Substitution Vollhardt 17.00 - Aldehydes and Ketones Vollhardt 18.00 - Enolate Chemistry Vollhardt 18.50 - Organometallic Addition, Conjugate Addition Vollhardt 18.50 - Aldol Chemistry and Michael Addition Vollhardt 19.50 - Redox of Alcohols and Carbonyls Vollhardt 20.00 - Carboxylic Acid Derivatives Vollhardt 21.00 - Amines Vollhardt 22.00 - Reactions of Substituted Benzenes Vollhardt 22.50 - Arenediazonium Reactions Vollhardt 23.00 - Claisen Condensations Vollhardt 23.50 - Acetoacetic and Malonic Ester Synthesis Vollhardt 24.00 - Carbohydrates Vollhardt 26.00 - Amino Acid Synthesis Vollhardt 26.50 - Peptide Synthesis Bruice 4.00 - Alkenes Bruice 6.00 - Alkynes Bruice 8.00 - Dienes, Conjugation, Diels-Alder Bruice 9.00 - Alkanes, Radical Reactions Bruice 10.00 - Substitution (Nucleophilic) of Alkyl Halides Bruice 11.00 - Elimination Reactions of Alkyl Halides Bruice 12.00 - Alcohols and Epoxides Bruice 12.50 - Epoxides and Organometallic Compounds Bruice 15.00 - Electrophilic Aromatic Substitution Bruice 16.00 - Reactions of Substituted Benzenes Bruice 16.50 - Arenediazonium Reactions Bruice 16.75 - SnAr and Benzyne Reactions Bruice 17.00 - Carboxylic Acid Derivatives Bruice 18.00 - Aldehydes and Ketones Bruice 18.50 - Organometallic Addition, Conjugate Addition Bruice 18.80 - Protecting Groups and Hydride Addition Bruice 19.00 - Acetoacetic and Malonic Ester Synthesis Bruice 19.00 - Enolate Chemistry Bruice 19.50 - Claisen Condensations Bruice 19.50 - Aldol Chemistry and Michael Addition Bruice 20.00 - Redox of Alkenes and Alkynes Bruice 20.50 - Redox of Alcohols and Carbonyls Bruice 20.50 - Oxidation of Alcohols and Alkenes Bruice 21.00 - Amines Bruice 21.09 - Naphthalene and Heteroaromatic EAS Reactions Bruice 21.10 - Pyridine Derivatives Bruice 22.00 - Carbohydrates Bruice 23.00 - Peptide Synthesis Bruice 23.00 - Amino Acid Synthesis Bruice 29.00 - Pericyclic Reactions Maximum Steps	Not sure what parameters you need to setup a problem? Click on the Help link above for a general overview of the system, or point your cursor at any control and a brief description will appear here.
Mechanism Explorer Top User ID User Class -- Select -- Chem 51B - Winter 2009 - Freeman Chem 51B - Winter 2009 - King Chem 51B - Winter 2009 - Shea Chem 52B - Winter 2009 - Overman Chem 51A - 2008 - Examples Chem 51B - 2008 - Examples Chem 51C - 2008 - Examples Chem 52A - 2008 - Examples Chem 52B - 2008 - Examples Chem 52C - 2008 - Examples Chem 51A - 2008 - Recommended Chem 51B - 2008 - Recommended Chem 51C - 2008 - Recommended Chem 52A - 2008 - Recommended Chem 52B - 2008 - Recommended Chem 52C - 2008 - Recommended Demo Examples Mechanism Problem (Prepare Blank Mechanism) #081 [Smith 9.09, Loudon 10.01, Solomons 11.00] #008 [Smith 9.12, Loudon 10.03, Solomons 11.00] #134 [Smith 10.00, Loudon 5.00, Solomons 8.02] #071 [Smith 10.12, Loudon 5.03, Solomons 8.02] #072 [Smith 10.15, Loudon 5.01, Solomons 8.02] #073 [Smith 11.09, Loudon 14.05, Solomons 8.18] #131 [Smith 15.10, Loudon 17.02, Solomons 15.15] #132 [Smith 15.13, Loudon 5.05, Solomons 10.00] #074 [Smith 18.05, Loudon 16.04, Solomons 15.09] #076 [Smith 18.05, Loudon 16.04, Solomons 15.09] #075 [Smith 18.05, Loudon 16.04, Solomons 15.09] #133 [Smith 20.13, Loudon 21.10, Solomons 19.09] #077 [Smith 21.12, Loudon 19.11, Solomons 16.00] #078 [Smith 21.12, Loudon 19.11, Solomons 16.00] #080 [Smith 21.14, Loudon 19.08, Solomons 16.00] #079 [Smith 21.14, Loudon 19.08, Solomons 16.00] #084 [Smith 22.11, Loudon 21.08, Solomons 18.00] #085 [Smith 23.09, Loudon 22.07, Solomons 19.03] #086 [Smith 24.01, Loudon 22.04, Solomons 17.04] #083 [Smith 24.04, Loudon 22.04, Solomons 17.04] #082 [Smith 24.09, Loudon 22.08, Solomons 17.04] #032 [Loudon 18.05, Solomons 21.20] #033 [Loudon 25.04, Solomons 21.20] Textbook Any Smith 2nd ed. Loudon 4th ed. Solomons 9th ed. Vollhardt 5th ed. Bruice 4th ed. Reaction Subject Category Smith 7.00 - Substitution (Nucleophilic) of Alkyl Halides Smith 8.00 - Elimination Reactions of Alkyl Halides Smith 9.00 - Alcohols and Epoxides Smith 10.00 - Alkenes, Electrophilic Addition Smith 11.00 - Alkynes, Addition and Acetylide Ions Smith 12.00 - Redox of Alkenes and Alkynes Smith 12.12 - Oxidation of Alcohols and Alkenes Smith 15.00 - Alkanes, Radical Reactions Smith 16.00 - Dienes, Conjugation, Diels-Alder Smith 18.00 - Electrophilic Aromatic Substitution Smith 18.14 - Reactions of Substituted Benzenes Smith 20.12 - Redox of Alcohols and Carbonyls Smith 20.14 - Epoxides and Organometallic Compounds Smith 20.15 - Organometallic Addition, Conjugate Addition Smith 21.00 - Aldehydes and Ketones Smith 21.15 - Protecting Groups and Hydride Addition Smith 22.00 - Carboxylic Acid Derivatives Smith 23.00 - Enolate Chemistry Smith 23.09 - Acetoacetic and Malonic Ester Synthesis Smith 24.00 - Aldol Chemistry and Michael Addition Smith 24.05 - Claisen Condensations Smith 25.00 - Amines Smith 25.14 - Arenediazonium Reactions Smith 27.00 - Carbohydrates Smith 28.02 - Amino Acid Synthesis Smith 28.06 - Peptide Synthesis Loudon 5.00 - Alkenes Loudon 9.04 - Substitution (Nucleophilic) of Alkyl Halides Loudon 9.05 - Elimination Reactions of Alkyl Halides Loudon 10.00 - Alcohols and Epoxides Loudon 11.04 - Epoxides and Organometallic Compounds Loudon 11.05 - Oxidation of Alcohols and Alkenes Loudon 14.00 - Alkynes Loudon 15.00 - Dienes, Conjugation, Diels-Alder Loudon 16.00 - Electrophilic Aromatic Substitution Loudon 17.00 - Allylic and Benzylic Reactivity Loudon 17.02 - Alkanes, Radical Reactions Loudon 18.00 - Transition Metal (Pd) Catalysis Loudon 18.04 - SnAr and Benzyne Reactions Loudon 19.00 - Aldehydes and Ketones Loudon 20.10 - Redox of Alcohols and Carbonyls Loudon 21.00 - Carboxylic Acid Derivatives Loudon 22.00 - Acetoacetic and Malonic Ester Synthesis Loudon 22.00 - Enolate Chemistry Loudon 22.04 - Aldol Chemistry and Michael Addition Loudon 22.05 - Claisen Condensations Loudon 22.08 - Organometallic Addition, Conjugate Addition Loudon 23.00 - Amines Loudon 23.10 - Arenediazonium Reactions Loudon 24.00 - Naphthalene and Heteroaromatic EAS Reactions Loudon 24.05 - Pyridine Derivatives Loudon 25.00 - Pericyclic Reactions Loudon 26.04 - Amino Acid Synthesis Loudon 26.07 - Peptide Synthesis Loudon 27.00 - Carbohydrates Solomons 6.02 - Substitution (Nucleophilic) of Alkyl Halides Solomons 6.15 - Elimination Reactions of Alkyl Halides Solomons 8.02 - Alkenes, Electrophilic Addition Solomons 8.16 - Redox of Alkenes and Alkynes Solomons 8.18 - Alkynes, Addition and Acetylide Ions Solomons 10.00 - Alkanes, Radical Reactions Solomons 11.00 - Alcohols and Epoxides Solomons 12.03 - Redox of Alcohols and Carbonyls Solomons 12.04 - Oxidation of Alcohols and Alkenes Solomons 12.05 - Epoxides and Organometallic Compounds Solomons 13.00 - Dienes, Conjugation, Diels-Alder Solomons 15.00 - Electrophilic Aromatic Substitution Solomons 15.09 - Reactions of Substituted Benzenes Solomons 15.15 - Allylic and Benzylic Reactivity Solomons 16.00 - Aldehydes and Ketones Solomons 17.00 - Enolate Chemistry Solomons 17.04 - Aldol Chemistry and Michael Addition Solomons 18.00 - Carboxylic Acid Derivatives Solomons 19.02 - Claisen Condensations Solomons 19.03 - Acetoacetic and Malonic Ester Synthesis Solomons 19.09 - Organometallic Addition, Conjugate Addition Solomons 20.00 - Amines Solomons 20.06 - Arenediazonium Reactions Solomons 21.11 - SnAr and Benzyne Reactions Solomons 21.20 - Transition Metal (Pd) Catalysis Solomons 21.20 - Pericyclic Reactions Solomons 22.00 - Carbohydrates Solomons 24.03 - Amino Acid Synthesis Solomons 25.05 - Peptide Synthesis Vollhardt 3.00 - Alkanes, Radical Reactions Vollhardt 6.00 - Substitution (Nucleophilic) of Alkyl Halides Vollhardt 7.00 - Elimination Reactions of Alkyl Halides Vollhardt 9.00 - Oxidation of Alcohols and Alkenes Vollhardt 9.00 - Alcohols and Epoxides Vollhardt 12.00 - Alkenes Vollhardt 13.00 - Alkynes Vollhardt 13.50 - Redox of Alkenes and Alkynes Vollhardt 14.00 - Dienes, Conjugation, Diels-Alder Vollhardt 15.00 - Electrophilic Aromatic Substitution Vollhardt 17.00 - Aldehydes and Ketones Vollhardt 18.00 - Enolate Chemistry Vollhardt 18.50 - Organometallic Addition, Conjugate Addition Vollhardt 18.50 - Aldol Chemistry and Michael Addition Vollhardt 19.50 - Redox of Alcohols and Carbonyls Vollhardt 20.00 - Carboxylic Acid Derivatives Vollhardt 21.00 - Amines Vollhardt 22.00 - Reactions of Substituted Benzenes Vollhardt 22.50 - Arenediazonium Reactions Vollhardt 23.00 - Claisen Condensations Vollhardt 23.50 - Acetoacetic and Malonic Ester Synthesis Vollhardt 24.00 - Carbohydrates Vollhardt 26.00 - Amino Acid Synthesis Vollhardt 26.50 - Peptide Synthesis Bruice 4.00 - Alkenes Bruice 6.00 - Alkynes Bruice 8.00 - Dienes, Conjugation, Diels-Alder Bruice 9.00 - Alkanes, Radical Reactions Bruice 10.00 - Substitution (Nucleophilic) of Alkyl Halides Bruice 11.00 - Elimination Reactions of Alkyl Halides Bruice 12.00 - Alcohols and Epoxides Bruice 12.50 - Epoxides and Organometallic Compounds Bruice 15.00 - Electrophilic Aromatic Substitution Bruice 16.00 - Reactions of Substituted Benzenes Bruice 16.50 - Arenediazonium Reactions Bruice 16.75 - SnAr and Benzyne Reactions Bruice 17.00 - Carboxylic Acid Derivatives Bruice 18.00 - Aldehydes and Ketones Bruice 18.50 - Organometallic Addition, Conjugate Addition Bruice 18.80 - Protecting Groups and Hydride Addition Bruice 19.00 - Acetoacetic and Malonic Ester Synthesis Bruice 19.00 - Enolate Chemistry Bruice 19.50 - Claisen Condensations Bruice 19.50 - Aldol Chemistry and Michael Addition Bruice 20.00 - Redox of Alkenes and Alkynes Bruice 20.50 - Redox of Alcohols and Carbonyls Bruice 20.50 - Oxidation of Alcohols and Alkenes Bruice 21.00 - Amines Bruice 21.09 - Naphthalene and Heteroaromatic EAS Reactions Bruice 21.10 - Pyridine Derivatives Bruice 22.00 - Carbohydrates Bruice 23.00 - Peptide Synthesis Bruice 23.00 - Amino Acid Synthesis Bruice 29.00 - Pericyclic Reactions	To access random mechanism problems, click on the [Mechanism] button that appears for any predicted reaction from the Reaction Drills or Synthesis Explorer. Not sure what parameters you need to setup a problem? Click on the Help link above for a general overview of the system, or point your cursor at any control and a brief description will appear here.
User Records Top User Class -- Select -- Chem 51B - Winter 2009 - Freeman Chem 51B - Winter 2009 - King Chem 51B - Winter 2009 - Shea Chem 52B - Winter 2009 - Overman Chem 51A - 2008 - Examples Chem 51B - 2008 - Examples Chem 51C - 2008 - Examples Chem 52A - 2008 - Examples Chem 52B - 2008 - Examples Chem 52C - 2008 - Examples Chem 51A - 2008 - Recommended Chem 51B - 2008 - Recommended Chem 51C - 2008 - Recommended Chem 52A - 2008 - Recommended Chem 52B - 2008 - Recommended Chem 52C - 2008 - Recommended Demo Examples User ID	Not sure what parameters you need to setup a problem? Click on the Help link above for a general overview of the system, or point your cursor at any control and a brief description will appear here.
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